Simvastatin

Fig.: Separation of simvastatin.

Experimental conditions:
Instrument: Trisep-2010 GV CEC system;
Column: 200 mm×100μm I.D. capillary packed with 3μm C18 ;
Mobile phase: Methanol/water = 65/35;
Flow rate: 0.02 ml/min
Pressure applied on column: 7 Mpa;
Injection volume: 10 nl;
Detector wavelength: UV 238 nm;
Peaks: 1. simvastatin