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Selected Publications

Chiral compound

• Chiral recognition ability of (S)-napr0xen imprinted monolith by capillary electrochromatograph.
  YanLi Xu ZhaoSheng Liu, Hefang Wang, Chao Yan, Ru-Yu Gao. Electrophoresis, 2005，26 (4-5): 804-811 .
• Renal D-Amino Acid Oxidase Mediates Chiral Inversion of NG-Nitro-D-arginine.
  YanFei Xin, XiangJun Zhou, Xi Cheng, YongXiang Wang. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2005, 312:1090–1096.
• Pressurized Capillary Electrochromatography:Theory, Mechanism, and Application in Enantiomeric Separations.
  Chuanyi Yao, Kai Zhang, Ruyu Gao, Chun Jiang, Yukui Zhang, Chao Yan. Anal. Chem., 2004
• Preparation and characterization of molecularly omprinted monolithic column using 4-hydroxybenzoic acids as templates for capillary electrochromatography.
  ZhaoSheng Liu, YanLi Xu, Chao Yan, RuYu Gao. Analytica Chimica Acta, 2004, 523 (2): 243-250.
• Chiral Separation of Binaphthol Enantiomers on Molecularly Imprinted Polymer Monolith by Capillary Electrochromatography.
  ZhaoSheng Liu, YanLi Xu, Chao Yan, RuYu Gao. Analytical Sciences, 2004, 20(4), 673-678
• Capillary electrochromatography of molecularly imprinted monolithic column using p-hydroxybenzoic acid as templates.
  ZhaoSheng Liu, YanLi Xu, Chao Yan, Ru-Yu Gao. Chinese Chemical Letters, 2004, 15 (12): 1469-1472.
• Capillary Electrochromatographic Separation of Ionizable Compounds with Molecular Imprinted Monolithic Column.
  Weiying Yan, Ruyu Gao, Chao Yan. J. Sep. Sci. 2003, 26, 1.
• Enantioseparations in Non-aqueous Media of Chiral Pharmaceuticals by Pressurized Capillary Electrochromatography.
  Lei Kang, Chuanyi Yao, Chao Yan and Ruyu Gao. Chemical Journal of Internat, 2002, 4 (12), 58.
• Enantiomeric separations of 1-1,2,4-triazole compounds by micro-high performance liquid chromatography.
  Chao Yan, Chinese J. of Chromatogr. 2001, 19(3), 253.
• Enantiomer separations of phenylephrine and synephrine by capillary electrochromatography on bare silica stationary phase using hydroxypropyl-b-cyclodextrin as a mobile phase additive.
  Wei, Wei; Luo, Guoan; Xiang, Rong; Yan, Chao. J. Microcol. Sep., 1999, 11(4), 263.
• Enantiomeric Separation of ß Amine Alcohols by Capillary Zone Electrophoresis Using Cyclodextrin as Chiral Selector.
  Wei, W.; Luo, G. A.; Yan, C. J. High Resol. Chromatogr., 1998, 21(8), 440.
• Capillary electrochromatography: operating characteristics and enantiomeric separations. Lelievre, Frederic;
  Yan, Chao; Zare, Richard N. J. Chromatogr., A, 1996. 723(1), 145.

Life science

• Pressurized Electrochromatography Coupled with Electrospray Ionization Mass Spectrometry for Analysis of Peptides and Proteins.
  Zhen Liang, Jicheng Duan, Lihua Zhang, Weibing Zhang, Yukui Zhang, Chao Yan. Anal. Chem., 2004; 76，6935–6940.
• Pressurized Electrochromatography Coupled with Electrospray Ionization Mass Spectrometry for Analysis of Peptides and Proteins.
  Zhen Liang, Jicheng Duan, Lihua Zhang, Weibing Zhang, Yukui Zhang, Chao Yan. CCE 2004, Oct. 20, 2004, Beijing.
• CEC and its Application in Analysis of Biological Samples Chapter 7 in Book: Modern Methods of Separation and Analysis for Biological Samples.
  Zhengjin Jiang, Vernon Jiang and Chao Yan, Editor: Yukui Zhang, Science Publishing Co., 2003
• Sepatation of peptides by pressurized capillary electrochromatoraphy.
  Kai Zhang, Chao Yan, Chunyi Yao, Ruyu Gao. J.of Chromatogr. A., 2003, 987, 453-458
• Pressurized Capillary Electrochromatography Separation of Peptides with Strong Cation Exchange and Hydrophilic Interaction.
  Kai Zhang, Ruyu Gao, Zhengjin Jiang, Chuanyi Yao, Zhichao Zhang, Qinsun Wang, Chao Yan. J. Sep.Sci. 2003, 26, 1389.
• Separation of Peptides by pressurized capillary electrochromatography
  Kai Zhang, Chao Yan, Zhichao Zhang, QinSun Wang, Ruyu Gao. Chinese Chemical Letters, 2003, 14, 611-614.
• Separation of Peptides by Reversed Phase pCEC.
  Kai Zhang, Chao Yan, Zhichao Zhang, Qinsun Wang, Ruyu Gao. Journal of Instrumental Analysis. 2003, 22 (3), 32.
• Pressurized gradient capillary electrochromatographic separation of eighteen amino acid derivatives.
  Ru, Q.-H.; Yao, J.; Luo, G.-A.; Zhang, Y.-X.; Yan, C. J. Chromatogr., A, 894(1+2), 337, 2000
• Investigation on Separation of Peptides by SCX-Capiilary Electrochromatography.
  Kai Zhang, Zhichao Zhang, Qinsun Wang, Ruyu Gao, Chuanyi Yao, Zhengjin Jiang, Wenyu Xue, Chao Yan. Analytical Laboratory. 2001, 20,142.
• Separation of Nucleosides by Capillary Electrochromatography.
  Zhengjin Jiang, Ruyu Gao, Zhichao Zhang, Kai Zhang, Qinsun Wang,and Chao Yan,BCEIA ( 9th Beijing Conference and Exhibition on Instrumental Analysis) (2001)D141
• Pressurized Capillary Electrochromatographic Separation of Five Peptides
  Kai Zhang Zhengjin Jiang, Chuany Yao and Wenyu Xue,Ruyu Gao, Chao Yan,BCEIA ( 9th Beijing Conference and Exhibition on Instrumental Analysis) (2001)D149

Pharmaceutical

• Mixed Mode of Hydrophilic and Ionic Interaction Pressurized Capillary Electrochromatography for Separation of Basic Compounds.
  Kai Zhang, Chao Yan, Zhichao Zhang, Qinsun Wang, Ruyu Gao. J. of Liquid Chromatogr., 2003, 26 (13), 2119.
• Separation of Basic Drugs using Pressurized Capillary Electrochromatography.
  Kai Zhang, Chao Yan, Chuanyi Yao, Zhengjin Jiang, Zhichao Zhang, Qinsun Wang, Ruyu Gao. Chinese J. of Chemistry, 2003, 21(4): 419.
• Separation of related opiate compounds using capillary electrochromatography.
  Lim, Jong-Tae; Zare, Richard N.; Bailey, Christopher G.; Rakestraw, David J.; Yan, Chao. Electrophoresis, 21(4), 737, 2000
• Capillary electrochromatographic separation of basic compounds with bare silica as stationary phase.
  Wei, W.; Luo, G. A.; Hua, G. Y.; Yan, C. J. Chromatogr., A, 1998, 817(1 + 2), 65.

Chemica l& Petrochemical

• Application of Gradient Pressurized Capillary Electrochromatography.
  Kai Zhang, Chao Yan, Zhichao Zhang, Qinsun Wang, Ruyu Gao. Chinese Chemical Letters, 2003, 14 (6), 611.
• Gradient pressurized CEC separation of six peptides,
  Kai Zhang, Zhengjin Jiang, Chuany yao, Wenyu Xue, Ruyu Gao , Chao Yan. 26th International Symposium on HPLC and Relative Techniques (2002) Montreal, Canada, No.99
• Separation of pyridazinone derivatives using pressurized gradient capillary electrochromatography.
  Jiang, Zhengjin; Gao, Ruyu; Zhou, Yibo; Zhang, Zhichao; Wang, Qinsun; Yan, Chao. Journal of Microcol. Sep., 2001, 13 (5), 191.
• Sensitive, universal detection for capillary electrochromatography using condensation nucleation light scattering detection.
  Guo, Wei; Koropchak, J. A.; Yan, Chao. J. Chromatogr., A, 1999, 849(2), 587.
• Gradient elution in capillary electrochromatography.
  Anex, Deon; Rakestraw, David J.; Yan, Chao; Dadoo, Rajeev; Zare, Richard N. [Tech. Rep.] SAND, SAND97-8276, 1-3, 5-26, 1997.
• Gradient Elution in Capillary Electrochromatography.
  Yan, Chao; Dadoo, Rajeev; Zare, Richard N.; Rakestraw, David J.; Anex, Deon S. Anal. Chem., 1996, 68(17), 2726.

Natural product

• Separation of Green Tea Extract by Pressurized Capillary Electrochromatography ( pCEC)
  Xiuli Wang, Junjiao YANG, Ping Fang, Xuehua Jiang, Yukui ZHANG and Chao YAN,Proceedings of International Beijing Conference and Exhibition on Instrumental Analysis, Beijing, China, Oct. 13-16, 2003
• Separation of green tea extract by pressurized capillary electrochromatography
  Xiuli WANG, Junjiao YANG, Ping FANG, Xuehua JIANG, Yukui ZHANG and Chao YAN. Proceedings of International 10th Beijing Conference and Exhibition on Instrumental Analysis, D95 October, 2003, Beijing, China

Environment

• Development of a Precolumn Derivatization Method for the Determination of Free Amines in Wastewater by High-Performance Liquid Chromatography via Fluorescent Detection with 9-(2-Hydroxyethyl) acridone.
  Jinmao You, Weibing Zhang, Qinghe Zhang, Lin Zhang, Chao Yan, Yukui Zhang. Anal. Chem., 2002, 74(1), 261.
• Determination of sulfonylurea herbicides by capillary electrochromatography.
  Lopez-Avila, Viorica; Benedicto, Janet; Yan, Chao. J. Chromatogr. Sci., 1999, 37(5), 165.
• Advances in Capillary Electrochromatography: Rapid and High-Efficiency Separations of PAHs.
  Dadoo, Rajeev; Zare, Richard N.; Anex, Deon S.; Yan, Chao. Anal. Chem., 1998, 70(22), 4787.
• Separation of Explosives Using Capillary Electrochromatography.
  Bailey, Christopher G.; Yan, Chao. Anal. Chem., 1998, 70(15), 3275.
• Capillary electrochromatographic retention behavior of several aromatic compounds on cyanopropyl-bonded phase.
  Wei, Wei; Wang, Yiming; Luo, Guo'an; Zhou, Yuhua; You, Huiyan; Yan, Chao. Chinese Journal of Chromatography, 1998, 16(6), 520.
• Determination of selected heterocyclic compounds containing nitrogen, oxygen, and sulfur by capillary electrochromatography.
  Lopez-Avila, Viorica; Benedicto, Janet; Yan, Chao. J. High Resolut. Chromatogr., 1997, 20(11), 615.
• Capillary Electrochromatography: Analysis of Polycyclic Aromatic Hydrocarbons.
  Yan, Chao; Dadoo, Rajeev; Zhao, Hui; Zare, Richard N.; Rakestraw, David J. Anal. Chem., 1995, 67(13), 2026.
• Molecular theory of chromatography for blocklike solutes in isotropic stationary phases and its application to supercritical fluid chromatographic retention of PAHs.
  Yan, Chao; Martire, Daniel E. J. Phys. Chem., 1992, 96(19), 7510.
• Determination and theoretical analysis of supercritical fluid chromatographic retention of polycyclic aromatic hydrocarbons in a polymeric smectic phase.
  Yan, Chao; Martire, Daniel E. J. Phys. Chem., 1992, 96(8), 3505.

Column

• Preparation and Evaluation of Polymer-Encapsulated Zirconia-Based Packings for HPLC.
  Junjiao Yang, Yumin Zuo, Yukui Zhang,Chao Yan. J. Sep. Sci., Submitted, 2004
• Synthesis of Porous Zirconia Spheres by Polymerization Induced Colloid Aggregation and Its Application in HPLC and CEC.
  Junjiao Yang, Zhengjin Jiang, Yumin Zuo, Yukui Zhang, Chao Yan. J. Sep. Sci., Submitted, 2004
• Preparation of Monolithic Column and Its Application in p-CEC.
  Jun Jiao Yang, Kai Zhang, Ru Yu Gao, Yu Kui Zhang, Chao Yan. Chinese Chemical Letters, 2004, 15, 435-438.
• Preparation and evaluation of C16 monolith columns for capillary electrochromatography.
  Kai Zhang, Chao Yan, RuYu Gao. Separation science 2004,
• Investigation of reversed phase polyacrylamide based monolithic polymer columns for capillary electrochromatography and pressure electrochromatography.
  Kai Zhang, Chao Yan, Ruyu Gao. 26th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 2004, Oct, Paris.
• Cinnamic Acid Polymer-based Monolithic Column for Capillary Electrochromatography
  Weiying Yan, Ruyu Gao, Zhichao Zhang, Chao Yan, Qingsun Wang. Cromatographia, 2003, 57 (11), 819.
• Preparation of Monolithic Column and Its Application in p-CEC
  Junjiao YANG, Xiuli Wang, Yukui ZHANG, Chao YAN,Proceedings of International Beijing Conference and Exhibition on Instrumental Analysis, Beijing, China, Oct. 13-16, 2003
• Preparation of monolithic column and its application in pCEC
  Junjiao YANG, Xiuli WANG, Ping FANG, Yukui ZHANG and Chao YAN, Proceedings of International 10th Beijing Conference and Exhibition on Instrumental Analysis, D91, October, 2003, Beijing, China
• Short, Highly Cross-linked, Polymer based Monolithic column for Capillary Electrochromatography.
  Weiying Yan, Zhichao Zhang, Ruyu Gao, Chao Yan, Qinsun Wang. J. Of Liq. Chromatogr. & Related Technologies, 2002, 25 (19), 2963.
• Capillary electrochromatography on unmodified silica gel packed column with reversed elution.
  Wei, Wei; Wang, Yiming; Luo, Guoan; Yan, Chao. Chinese J. Anal. Chem., 1998, 26(3), 287.
• Ion-exchange capillary electrochromatography with a strong cation exchanger packed column.
  Wei, Wei; Luo, Guoan; Yan, Chao Am. Lab., 1998, 30(1), 20C-20E.
• Electrochromatography and micro high-performance liquid chromatography with 320 mm I.D. packed columns.
  Yan, Chao; Schaufelberger, Daniel; Erni, Fritz. J. Chromatogr., A, 1994, 670(1-2), 15.
• Molecular theory of chromatographic selectivity enhancement for blocklike solutes in anisotropic stationary phases and its application.
  Yan, Chao; Martire, Daniel E. Anal. Chem., 1992, 64(11), 1246.
• Molecular theory of chromatography for blocklike solutes in anisotropic stationary phases and its application.
  Yan, Chao; Martire, Daniel E. J. Phys. Chem., 1992, 96(8), 3489.
• Determination of the hold-up time and column outlet density for capillary supercritical fluid chromatography.
  Riester, R. L.; Yan, C.; Martire, D. E. J. Chromatogr., 1991, 588(1-2), 289.

Overview

• Preparation of Capillary Monolithic Column and Its Application in pCEC.
  Jun Jiao YANG, Yukui Zhang, Chao YAN. J. Sep. Sci., Submitted, 2004
• Preparaton and evaluation of a series of reversed phase monolithic columns for capillary.
  Kai Zhang, Chao Yan, RuYu Gao. Anal. Lett., 2004, 37(11), 2363-2377.
• Capillary Electrochromatography: Advances in Instrumentation and Stationary Phases.
  Chao Yan, Xiuli Wang, Ruyu Gao, Yukui Zhang. Invited Speaker, 227th ACS National Meeting, Anaheim, CA, March 28-April 1, 2004.
• Recent Development in Capillary Electrochromatography.
  Chao Yan, Zhen Liang, Xiuli Wang, Yukui Zhang. 7th Sino-German Symposium on Chromatography, Oct. 17-22, 2004, ChongQing, China.
• Quantitative Sample Injection for Capillary Electrophoresis.
  Chuanyi Yao, Ruyu Gao, Chao Yan. J. Sep. Sci. 2003, 26(1-2), 37.
• Advances in Pressurized Capillary Electrochromatography: Theory, Instrumentation, Column and Applications.
  Chao YAN, Junjiao YANG, Chuanyi Yao, Yukui ZHANG, Kai ZHANG and Ruyu Gao. Proceedings of International Beijing Conference and Exhibition on Instrumental AnalysiBeijing, China, Oct. 13-16, 2003
• Advances in pressurized capillary electrochromatography: theory, instrumentation, column and applications
  Chao YAN, Junjiao YANG, Chuanyi YAO, Yukui ZHANG, Kai ZHANG, and RuyuGAO, Proceedings of International 10th Beijing Conference and Exhibition on Instrumental Analysis D63, October, 2003, Beijing, China
• Recent Advances in Capillary Electrochromatography.
  Chao Yan, Ruyu Gao, Yukui Zhang. Invited Speaker, International Symposium on Nano-Technology and Bioanalysis, Changsha, China, October 2002.
• Calculation of retention factors for charged solutes in capillary electrochromatography.
  WeiWei Luo, Guoan, Chao Yan. J. Sep. Sci., 2001, 24(3), 203.
• Advances in Capillary Electrochromatography.
  Chao Yan. Invited Speaker, 4th International Symposium on Capillary Electrochromatography, San Francisco, CA, 2001.
• Capillary Electrochromatography:Advances in Instrumentation and Applications.
  Chao Yan, Chuangi Yao, Zhengin Jiang, Kai Zhang, Ruyu Gao. BCEIA (9th Beijing Conference and Exhibition on Instrumental Analysis) (2001) D137
• Capillary Electrophoresis with Quantitative Sample Introduction
  Chuanyi Yao, Ruyu Gao,Chao Yan,BCEIA (9th Beijing Conference and Exhibition on Instrumental Analysis) (2001)D145
• Capillary Electrochromatography and Its Applications.
  Chao Yan. Invited Speaker, 2nd International Symposium on Capillary Electrochromatography, San Francisco, CA, 1999.
• Retention prediction based on the solvatochromic comparison method in reversed-phase capillary electrochromatography.
  Wei, W.; Wang, Y. M.; Luo, G. A.; Wang, R. J.; Guan, Y. H.; Yan, C. J. Liq. Chromatogr., 1998, 21(10), 1433.
• An Review on Capillary Electrochromatography.
  Chao Yan. Invited Speaker, 1st International Symposium on Capillary Electrochromatography, San Francisco, CA, 1998.
• Advances toward the routine use of capillary electrochromatography.
  Dadoo, Rajeev; Yan, Chao; Zare, Richard N.; Anex, Deon S.; Rakestraw, David J.; Hux, Gary A. LC-GC, 1997, 15(7), 630-632, 634.
• A Review of the Development of Capillary Electrochromatography.
  Wei, W.; Wang, Y. M.; Luo, G. A.; Yan, C. Chin. J. Anal. Chem., 1997, 25, 361.
• Investigation on Separating Behavior in Capillary Ion Exchange Electrochromatography.
  Wei, W.; Luo, G. A.; Yan, C.; Chin. J. Anal. Chem., 1997, 15, 110.
• Automated capillary electrochromatography: reliability and reproducibility studies.
  Dulay, Maria T.; Yan, Chao; Rakestraw, David J.; Zare, Richard N. J. Chromatogr., A, 1996, 725(2), 361.

Patents

1. Multiuse Pressure Electric Chromatographic Device.
   Yan, Chao. US Patent, 6,569,325, 2003

2. Quantitative gradient pressurized capillary electrophoresis device
   Chao Yan, Chuanyi Yao, CH Patent. ZL 01219839.0, 2002.
3. Multiple lane pressurized capillary electrochromatography device for biological analysis
   Chao Yan, CH Patent. ZL 01219840.4, 2002.
4. Multiple purpose pressurized electrochromatography device.
   Chao Yan, CH Patent. ZL 99206093.1, 2000.
5. Electro-osmotically driven liquid delivery method and apparatus.
   Rakestraw, David J.; Anex, Deon S.; Yan, Chao; Dadoo, Rajeev; Zare, Richard N. US Patent. 5,942,093 , 1999
6. Electrokinetic packing of capillary columns.
   Chao Yan, US Patent. 5453163, 1995